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Analytical capabilities for excipients

Aug  1, 2018

During summer 2018, VelaLabs has further expanded analytical capabilities for excipients in biopharmaceutical formulations.

A typical example for VelaLabs`s analytical capabilities for excipients in biopharmaceutical formulations is the use of a mixed-mode HPLC method with light scattering detection (ELSD) to quantitate the entirety of polysorbate species. Using QTOF mass spectrometry we can now additionally offer characterization of the esterified and un-esterified sorbide- and isosorbide species of polysorbates. Furthermore, we are currently working on setting up GC-MS methods to characterize the fatty acid compositions of different polysorbates.

Triple TOF and Agilent 1290 Infinity II

Typical chromatogram

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