Physico-chemical analysis

The physico-chem­ical labo­ra­tory supports Pharma and Biotech compa­nies with a wide variety of methods to deter­mine prop­er­ties of ATMPs, Vaccines, biophar­ma­ceu­ti­cals e.g. anti­bodies, biosim­i­lars, and chem­i­cals in liquid formu­la­tions via qual­i­fied or vali­dated U(HPLC) methods according to ICH Q2R1.

Excip­ient deter­mi­na­tion e.g. Polysor­bate 20, Polysor­bate 80, Polox­amer via Evap­o­rating Light Scat­tering Detector (ELSD)

(Ultra) High Perfor­mance Liquid Chro­matog­raphy via UV/VIS or ELSD

  • Size Exclu­sion Chro­matog­raphy (SEC)
  • Reversed Phase Chro­matog­raphy (RPC)
  • Cation/​Anion Ion Exchange (IEX)
  • Hydrophilic Inter­ac­tion Chro­matog­raphy (HILIC)
  • Hydrophobic Inter­ac­tion Chro­matog­raphy (HIC)

Wet chem­istry methods according to ph. eur. / USP e.g.

  • pH deter­mi­na­tion
  • Osmo­lality
  • Sub-Visible parti­cles (Partic­ular matter)
  • Coloration (device based)
  • Turbidity (device based)
  • Density deter­mi­na­tion (device based)
  • Endo­toxin determination
  • Visible Parti­cles
  • Extractable Volumes
  • Concen­tra­tion deter­mi­na­tion (OD280)
  • Conduc­tivity
  • TOC (Total Organic Carbon)

Mole­c­ular Biology methods

  • Gel Elec­trophoresis
    • Western Blot, SDS-Page (reducing/​non reducing), IEF-Page, Agarose elec­trophoresis for RNA/DNA separation
  • CE (Capil­lary Electrophoresis) 
    • cIEF, CZE, CE-SDS
  • Poly­merase Chain Reac­tion (PCR):
    • Real Time – PCR, quan­ti­ta­tive PCR
We Value Your Privacy
We use cookies on our website. Some of them are essential, while others help us to analyze how this website is being used and to allow you to contact us through our website, i.e. use the chat widget. You can change your decision at any time.
Privacy Settings
Statistics
We use these technologies to analyze how this website is being used.
Name Google Analytics, Google Tag Manager
Provider Google Ireland Limited, Gordon House, Barrow Street, Dublin 4, Ireland
Purpose Cookie by Google used for website analytics. Generates statistical data on how the visitor uses the website.
Privacy Policy https://policies.google.com/privacy
Cookie Name _ga, _gat, _gid
Cookie Expiry 2 years

 

Name LinkedIn Corporation
Provider LinkedIn Corporation, 605 W Maude Ave, Sunnyvale, CA 94085, USA
Purpose Cookie by LinkedIn used for website analytics. Generates statistical data on how the visitor uses the website.
Privacy Policy https://www.linkedin.com/legal/privacy-policy
Cookie Name
Cookie Expiry 2 years
Customer Interaction
These technologies will allow you to contact us through our website, i.e. use the chat widget.
Name LiveChat
Provider LiveChat Software S.A., ul. Zwycięska 47, 53-033 Wroclaw, Poland
Purpose Communication with clients via online chat using the API of the chat service LiveChat.
Privacy Policy https://www.livechat.com/legal/privacy-policy/
Cookie Name __lc_cid, __lc_cst
Cookie Expiry 2 years
Essential
Technologies required to enable the core functionality of this website.
Name Cookie Consent
Provider Owner of this website, Imprint
Purpose Saves the visitors preferences selected in the cookie banner.
Cookie Name ws_cookie_consent
Cookie Expiry 1 year