June 2021: With MALDI-TOF mass spectrometry (Matrix Assisted Laser Desorption lonization – Time of Flight) VelaLabs extends its’ method portfolio for germ identification in the field of microbiology.
The method combines matrix-assisted laser desorption ionization (MALDI) with time of flight (TOF) of released ions for mass spectrometry. The bacterial species is identified via the spectrum of the bacterial proteome after protein ionization and analysed with a database.
MALDI-TOF advantages in bacteriology
Over more than 10 years MALDI-TOF is used for germ identification. It has significant advantages in terms of
Studies show that MALDI-TOF is a suitable tool for being used in clinical and pharmaceutical bacteriology for identification of bacteria and bacterial toxin as well as antibiotic resistance.
Studies & more information:
- MALDI mass spectrometry imaging in oncology
- Matrix-assisted laser desorption ionization–time of flight mass spectrometry for identification of bacteria isolated from pharmaceutical clean rooms in: Interventional Medicine and Applied Science Volume 10 Issue 1 (2018) (akjournals.com)
- MALDI-TOF Mass Spectroscopy Applications in Clinical Microbiology (hindawi.com)
- Applications of MALDI-TOF mass spectrometry in clinical diagnostic microbiology | FEMS Microbiology Reviews | Oxford Academic (oup.com)
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