Classical bioassays may be categorized into in vivo and in vitro assays. In vivo bioassays involve the administration of the biotech agent to animals with subsequent measurement of the response in the animal. Drawbacks of this method include relatively high cost, lack of specificity, high inter-animal variability, and significant time requirements. In vitro bioassays are typically based upon a quantifiable cellular response to stimulation with the test agent. With the advent of immortal cell lines, in vitro bioassays offer the advantage of low assay variability when compared to in vivo methods.

Vela has extensive knowledge of the scientific principles relevant to bioassay analysis on proteins such as cell-based and biochemical binding assays. Vela has the technological resources to custom design the best bioassay for your product and solves assay development challenges relevant to most indication and every type of biologic product.